Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). It is also known as NUROFEN, FENPAED. Please read all information below to ensure safe dosage and correct medication is used.
• USE PARACETAMOL FIRST TO REDUCE FEVER AND PAIN IN CHILDREN
• Ibuprofen may be more effective when taken without food, with similar tolerability
• Dose according to weight rather than age; ibuprofen is not recommended for infants less than 6 months
• Ibuprofen is as or more efficacious than paracetamol (relatively small difference), and is equally safe
• Appropriate therapeutic doses are remarkably free of adverse effects but long-term safety is unknown
When to treat Fever and Pain in my child?
• Use Paracetamol if the child appears distressed or unwell
• Use ibuprofen (Nurofen, Fenpaed) if there is no response to Paracetamol
• Do not routinely use paracetamol and ibuprofen together at the same time, or alternately
• Regardless of which analgesic/antipyretic, use only if necessary for the shortest period of time to control symptoms.
Paracetamol or Ibuprofen (Nurofen, Fenpaed)?
• Paracetamol has analgesic (pain relief) and antipyretic(reduces fever) but no anti-inflammatory activity; it is less irritant to the stomach than Ibuprofen.
• Ibuprofen (Nurofen, Fenpaed) has anti-inflammatory effects, and may be more effective than paracetamol in pain reduction in diseases in which inflammation is a major cause of tissue injury, such as juvenile rheumatic arthritis.
• There is a relatively small difference in analgesic and antipyretic efficacy or adverse effects between paracetamol and intermittent oral dosing of ibuprofen.
• For children without underlying medical conditions, or with underlying medical conditions that are not inflammatory in nature, beginning treatment with oral paracetamol is preferred because of its long track record of safety.
• DO NOT USE BOTH PARACETAMOL AND IBUPROFEN COMBINATION/ALTERNATING REGIMES. If the decision is made to use a non-steroidal anti-inflammatory drug (NSAID) for a child , ibuprofen is preferred because it is equally effective and has fewer adverse effects than other NSAIDs.
• Onset of action less than60 minutes
• Peak effect (decline in temperature of 1-2°C) in 3-4 hours
• Duration of action is 6-8 hours
• Dose according to weight rather than age
• Gastrointestinal disturbances including discomfort, nausea, diarrhoea, and occasionally bleeding and ulceration
• IgE-mediated allergic reactions e.g. allergic rhinitis, rash, urticaria; and other severe hypersensitivity reactions e.g. angioedema and bronchospasm. N.B. caution in children with history of hypersensitivity to any NSAID i.e. attacks of asthma, angioedema, urticaria, rhinitis
• Worsening of asthma, either acutely or as a gradual worsening of symptoms. Children with asthma should preferably use paracetamol
• Renal function impairment; caution children with cardiac impairment
• Aseptic meningitis; rare but children with connective tissue disorders such as systemic lupus erythematosus may be especially susceptible.